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Medical News Article on Dementia Therapy

Studies from ChungNam National University, Center for Nanotechnology further understanding of dementia therapy

2010 FEB 8 -- Scientists discuss in 'Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia' new findings in dementia. "The aim of this study was to develop a pH-independent extended release matrix tablet of minocycline HCl for the treatment of dementia. The matrix tablets were prepared by wet granulation technique using Eudragit L and S as release modifiers at different w/w ratios (1:0, 1:1 and 0:1) and PEO as a matrix former," scientists in Korea report.

"In the case of the matrix tablet without any release modifiers, the drug release rate at pH 1.2 was much higher than that of pH 7.4. By adding the...

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