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Medical News Article on University of Cincinnati Academic Health Center

'Starving' fat suppresses appetite

2010 MAR 1 -- Peptides that target blood vessels in fat and cause them to go into programmed cell death (termed apoptosis) could become a model for future weight-loss therapies, say University of Cincinnati (UC) researchers.

A research team led by Randy Seeley, PhD, of UC's Metabolic Diseases Institute, has found that obese animal models treated with proapoptotic peptide experienced decreased food intake and significant fat loss.

The study was published online ahead of print Jan. 26, 2010, in Diabetes, the official journal of the American Diabetes Association.

White adipose (fat) tissue is vascularized, much like a tumor, and...

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