Researchers' work from Merck & Company, Inc., Department of Molecular focuses on atherosclerosis

2010 JUL 26 -- Researchers detail in 'Identification and validation of genes affecting aortic lesions in mice,' new data in atherosclerosis. According to a study from the United States, "Atherosclerosis represents the most significant risk factor for coronary artery disease (CAD), the leading cause of death in developed countries. To better understand the pathogenesis of atherosclerosis, we applied a likeli-hood-based model selection method to infer gene-disease causality relationships for the aortic lesion trait in a segregating mouse population demonstrating a spectrum of susceptibility to developing atherosclerotic lesions."

"We identified 292 genes that...

In order to view the entire article, please read your options to the right