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Medical News Article on Apraxia



Research on apraxia described by scientists at Queensland Institute of Medical Research



2007 JUL 30 -- Data detailed in "Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage" have been presented. "A defective response to DNA damage is observed in several human autosomal recessive ataxias with oculomotor apraxia, including ataxia-telangiectasia. We report that senataxin, defective in ataxia oculomotor apraxia (AOA) type 2, is a nuclear protein involved in the DNA damage response," scientists in Brisbane, Australia report.

"AOA2 cells are sensitive to H2 O2 , camptothecin, and mitomycin C, but not to ionizing radiation, and sensitivity was rescued with full-length...

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