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Medical News Article on Osteosarcoma Therapy



Data on osteosarcoma therapy described by researchers at National Institute of Health and Nutrition



2007 SEP 17 -- Investigators publish new data in the report "Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 43. Bowman-Birk protease inhibitor (BBI) from soybean acts as a potential chemopreventive agent in several types of tumors. However, the mechanism is still unclear," scientists in Tokyo, Japan report.

"The present study was undertaken to estimate a mechanism of BBI-dependent negative growth control of human osteosarcoma cell (U2OS cell). BBI had negative growth control of the cells via induction of connexin (Cx) 43, a tumor suppressor gene in U2OS cells. This negative growth...

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