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Medical News Article on Microbiology



Researchers from University of Warsaw, Institute of Microbiology describe findings in microbiology



2008 MAR 24 -- Research findings, 'Tip-alpha (hp0596 gene product) is a highly immunogenic Helicobacter pylori protein involved in colonization of mouse gastric mucosa,' are discussed in a new report. "A product of the Helicobacter pylori hp0596 gene (Tip-alpha) is a highly immunogenic homodimeric protein, unique for this bacterium. Cell fractionation experiments indicate that Tip-alpha is anchored to the inner membrane," scientists in Warsaw, Poland report.

"In contrast, the three-dimensional model of the protein suggests that Tip-alpha is soluble or, at least, largely exposed to the solvent. hp0596 gene knockout resulted in a significant decrease in...

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