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Medical News Article on DOE/Brookhaven National Laboratory



Structure reveals how cells 'sugar-coat' proteins



2008 MAR 24 -- Biologists at the U.S. Department of Energy's Brookhaven National Laboratory, Stony Brook University, and the University of Wurzburg, Germany, have deciphered the structure of a large protein complex responsible for adding sugar molecules to newly formed proteins - a process essential to many proteins' functions. The structure offers insight into the molecular "sugar-coating" mechanism, and may help scientists better understand a variety of diseases that result when the process goes awry. The research will appear in the March 12, 2008, issue of the journal Structure.

"Proteins perform their functions by interacting at their surfaces with other...

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