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Reports from Zhengzhou University advance knowledge in bioengineering
2008 MAY 5 -- "The expression of human alpha-1,2-fucosyltransferase (HT) or complement regulatory proteins has been proved as an strategy to overcome hypercute rejection in discordant xenogeneic organ transplantation. In this study, we examined whether peripheral blood mononuclear cells (PBMCs) from polytransgenic mice expressing the human HT, and complement regulatory proteins (DAF and CD59), can provide more effective protection against xenograft rejection," scientists writing in the journal Science in China Series C - Life Sciences report.
"Transgenic mice were produced by co-injection of gene constructs for human HT, DAF and/or CD59. Flow...
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