New atherosclerosis study findings have been reported from M.F. Engberink et al

   "We collected data on blood donation history and intima-media thickness of the common carotid artery (CIMT) in 819 subjects (50 - 70 years), who were recruited from municipal and blood bank registries in The Netherlands. Serum iron parameters were assessed, including non-transferrin bound iron (NTBI) that has recently been found in conditions of iron overload. Serum ferritin was lower in current donors (n=443; 441 mu g/L) than in ex-donors (n=120; 1141 mu g/L) and never-donors (n=256; 1241 mu g/L, P for trend < 0.001). For NTBI, values were 2.33, 2.54, and 2.51 mu mol/L, respectively (P < 0.05). CIMT was slightly reduced in frequent donors (i.e., >= 49 times during life or >= 2 times per year), although not statistically significant. CIMT was not significantly related to NTBI," wrote M.F. Engberink and colleagues.

   The researchers concluded: "Frequent blood donation, resulting in lowered body iron, might give some protection against accelerated atherosclerosis."

   Engberink and colleagues published the results of their research in Atherosclerosis (Blood donation, body iron status and carotid intima-media thickness. Atherosclerosis, 2008;196(2):856-862).

   For additional information, contact M.F. Engberink, POB 8129, NL-6700 EV Wageningen, Netherlands.

   The publisher of the journal Atherosclerosis can be contacted at: Elsevier Ireland Ltd., Elsevier House, Brookvale Plaza, East Park Shannon, Co. Clare, Ireland.

   Keywords: Netherlands, Angiology, Atherosclerosis, Blood Banking, Blood Transfusion, Cardiology, Cardiovascular, Cardiovascular Risk, Common Carotid Artery, Iron Overload, Transfusion Medicine.

   This article was prepared by Cardiovascular Week editors from staff and other reports. Copyright 2008, Cardiovascular Week via NewsRx.com.

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