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Findings from King Faisal Specialist Hospital and Research Center in cleft lip in children reported



December 9th, 2008

   2008 DEC 9 -- Scientists discuss in 'Pattern of cleft lip and palate in hospital-based population in Saudi Arabia: retrospective study' new findings in cleft lip. According to a study from Riyadh, Saudi Arabia, "To report the patterns of cleft lip and/or cleft palate in Saudi Arabia from data collected at a tertiary care hospital. King Faisal Specialist Hospital and Research Center, Riyadh."

   "All the cleft lip and/or cleft palate patients registered in the Cleft Lip/Palate and Craniofacial Anomalies Registry from June 1999 to December 2005. Retrospectively, 807 cases of cleft lip and/or palate were registered. There were 451 boys and 356 girls. Cleft lip and palate was more common (387) than isolated cleft palate (294) and isolated cleft lip (122). Boys predominated in cleft lip and palate and cleft lip; whereas, girls predominated in isolated cleft palate, with boy to girl ratios of 1.6:1, 1.2:1, and 0.9:1 for cleft lip and/or palate, isolated cleft lip, and isolated cleft palate, respectively. The Riyadh region had more cases (32.0%) than the Asir (15.6%) and Eastern (14.6%) regions. Parents of 439 individuals had consanguineous marriages. A positive family history of cleft was seen in 224 cases. Of 238 cases with associated anomalies, 91 had congenital heart disease. Of the children with isolated cleft palate, 40.5% had associated anomalies, whereas only 23.0% of the children with isolated cleft lip or cleft lip and palate had associated malformations," wrote A. Aljohar and colleagues, King Faisal Specialist Hospital and Research Center.

   The researchers concluded: "The pattern of cleft observed in this study does not differ significantly from those reported in the literature for Arab populations."

   Aljohar and colleagues published their study in Cleft Palate-Craniofacial Journal (Pattern of cleft lip and palate in hospital-based population in Saudi Arabia: retrospective study. Cleft Palate-Craniofacial Journal, 2008;45(6):592-6).

   For more information, contact A. Aljohar, King Faisal Specialist Hospital and Research Center, Dentistry Department, Riyadh, Saudi Arabia.

   Publisher contact information for the Cleft Palate-Craniofacial Journal is: Alliance Communications Group Division Allen Press, 810 East 10TH Street, Lawrence, KS 66044, USA.

   Keywords: Saudi Arabia, Riyadh, Cleft Lip, Cleft Palate, Craniofacial, Genetics.

   This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2008, Life Science Weekly via NewsRx.com.

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