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Medical News Article on Pharmacokinetics
Studies from Wyeth, Collegeville provide new data on pharmacokinetics
2008 JUL 21 -- Investigators publish new data in the report 'Evaluation of a potential tigecycline-warfarin drug interaction.' In this recent study, researchers in the United States conducted a study "To evaluate the potential for a clinically significant drug interaction between tigecycline and warfarin by using pharmacokinetic and anticoagulant assessments. Open-label, nonrandomized study."
"Inpatient clinical pharmacology unit. Nineteen healthy male volunteers were enrolled; eight completed all study assessments. All subjects received a single oral dose of warfarin 25 mg (day 1). Seven days later (day 8), they received a 100-mg loading dose of...
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