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Reports from Bristol-Myers Squibb Company advance knowledge in type 2 diabetes
2009 JUN 29 -- According to a study from the United States, "The study aim was to evaluate the efficacy and safety of initial combination therapy with saxagliptin + metformin vs. saxagliptin or metformin monotherapy in treatment-naive patients with type 2 diabetes (T2D) and inadequate glycaemic control. In this multicentre, randomized, double-blind, active-controlled phase 3 trial, 1306 treatment-naive patients with T2D >= 18 to <= 77 years, glycosylated haemoglobin (HbA1c ) >= 8 to <= 12%, fasting C-peptide concentration >= 1.0 ng/ml, body mass index <= 40 kg/m(2) were randomized to receive saxagliptin 5 mg + metformin 500 mg, saxagliptin 10 mg +...
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