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Medical News Article on Acute Myeloid Leukemia Therapy
Research on acute myeloid leukemia therapy discussed by scientists at University of Freiburg
2009 JUN 29 -- Fresh data on acute myeloid leukemia are presented in the report 'The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancergene expression in acute myeloidleukemia cells.' According to a study from Freiburg, Germany, "The three DNA methyltransferase (DNMT)-inhibiting cytosinenucleoside analogues, azacitidine, decitabine and zebularine, which are currently studied as nonintensive therapy for myelodysplastic syndromes and acute myeloid leukemia (AML), differ in structure and metabolism, suggesting that they may have differential molecular activity. We investigated cellular and molecular effects of the three...
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