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Immunization
Research from Novartis has provided new data on immunization
November 7th, 2009
According to recent research from Siena, Italy, "The goal of vaccination is to induce long-lasting protective immune memory. Although most vaccines induce good memory responses, the type of memory induced by different vaccines may be considerably different. in addition, memory responses to the same vaccine may be influenced by age, environmental and genetic factors." "emerging from detailed and integrated profiling of immune-responses to natural infection or vaccination suggest that the type and duration of immune memory are largely determined by the magnitude and complexity of innate immune signals that imprint the acquired immune primary responses. Here we summarize results obtained from analyzing human immune memory responses to different types of vaccines," wrote F. Castellino and colleagues, Novartis. The researchers concluded: "We will also discuss how extending clinical investigation to events occurring early after vaccination can help identify early predictive markers of protective memory and thus contribute to faster development of better and safer vaccines." Castellino and colleagues published their study in European Journal of Immunology (Generating memory with vaccination. European Journal of Immunology, 2009;39(8):2100-2105). For additional information, contact R. Rappuoli, Novartis Vaccines & Diagnostic Srl, Research Center, Via Fiorentina 1, I-53100 Siena, Italy. Publisher contact information for the European Journal of Immunology is: Wiley-V C H Verlag GmbH, PO Box 10 11 61, D-69451 Weinheim, Germany. Keywords: Italy, Siena, Biotechnology, Immunization, Immunology, Novartis AG, Pharmaceutical Business, Pharmaceutical Company, Vaccination, Vaccines, Novartis. This article was prepared by NewsRx editors from staff and other reports. Copyright 2009, NewsRx.com.
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