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Scientists at Labopharm, Inc. detail research in osteoarthritis
2009 NOV 2 -- "This analysis assesses the efficacy and safety of treatment with a once-daily oral formulation of tramadol for up to 12 weeks compared with placebo in women with moderate-to-severe pain due to osteoarthritis of the knee. Two parallel, placebo-controlled phase III clinical trials were analyzed; patients were randomized to a fixed dosage of Tramadol Contramid ® once a day (OAD) 100, 200, and 300 mg daily, or placebo," investigators in Laval, Canada report.
"The primary efficacy end points were the percentage difference from baseline of the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) subscale scores for pain and...
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