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Study data from University of Manchester provide new insights into life sciences
2009 NOV 3 -- New investigation results, 'Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci,' are detailed in a study published in Rheumatology. According to recent research from Manchester, the United Kingdom, "Five loci-the shared epitope (SE) of HLA--DRB1, the PTPN22 gene, a locus on 6q23, the STAT4 gene and a locus mapping to the TRAF1/C5 genetic region--have now been unequivocally confirmed as conferring susceptibility to RA. The largest single effect is conferred by SE."
"We hypothesized that combinations of susceptibility alleles may increase risk over and above that of...
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