Study Data from Max Planck Institute for Molecular Genetics Update Understanding of Receptor Protein-Tyrosine Kinases

2011 AUG 23 -- A new study, "Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region," is now available. According to the authors of recent research from Berlin, Germany, "Elongation of the digit rays resulting in the formation of a defined number of phalanges is a process poorly understood in mammals, whereas in the chicken distal mesenchymal bone morphogenetic protein (BMP) signaling in the so-called phalanx-forming region (PFR) or digit crescent (DC) seems to be involved. The human brachydactylies (BDs) are inheritable conditions characterized by variable degrees of digit shortening, thus...

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