"Here we show that more than half of primary ER+PR+ breast cancers contain an ER(-)PR(-)CK5(+) 'luminobasal' subpopulation exceeding 1% of cells. Starting from ER+PR+ luminal cell lines, we generated lines with varying luminal to luminobasal cell ratios and studied their molecular and biological properties. In luminal disease, luminobasal cells expand in response to...
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