Medical News Article on Ovarian Cancer

Findings from Netherlands Cancer Institute Provide New Insights into Ovarian Cancer

2012 APR 24 -- "Germline mutations in BRCA1/2 increase the lifetime risk for breast and ovarian cancer dramatically. Identification of such mutations is important for optimal treatment decisions and pre-symptomatic mutation screening in family members," researchers in Amsterdam, Netherlands report.

"Although current DNA diagnostics is able to identify many different mutations, it remains unclear, how many BRCA2-associated breast cancer cases remain unidentified as such. In addition, mutation scanning detects many unclassified variants (UV) for which the clinical relevance is uncertain. Therefore, our aim was to develop a test to identify BRCA2-association...

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