Medical News Article on Gene Therapy

Data from Beckman Research Institute Advance Knowledge in Gene Therapy

2012 MAY 1 -- Data detailed in "General principles of retrovirus vector design" have been presented. "An understanding in the life cycle of '-retroviruses has led to significant progress in the development of murine leukemia virus (MLV)-based vectors for gene delivery and human gene therapy. An MLV-based vector consists of the cis-acting sequences important for viral replication and gene expression," researchers in Duarte, California report.

"The sequence that encodes viral proteins is replaced with the gene of interest. To generate infectious retroviral vectors, viral-encoded proteins are supplied in trans for virion assembly. Here, we describe a method to...

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