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Medical News Article on Ovarian Cancer

DNA repair pathway score for predicting chemotherapy response in ovarian cancer patients

2012 MAY 4 -- A DNA repair pathway-focused score has the potential to help determine if first-line platinum based chemotherapy can benefit advanced-stage ovarian cancer patients, according to a study published April 13 in the Journal of the National Cancer Institute.

Most ovarian cancer patients are diagnosed with advanced disease (stages III and IV). They undergo surgery to remove as much tumor as possible, and then undergo platinum-based chemotherapy. But tools to predict response to platinum-based chemotherapy in ovarian cancer patients have been inadequate.

In order to determine if a DNA repair pathway-focused score could help...

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