Researchers from Washington University Publish New Studies and Findings in the Area of Molecular Imaging

2012 APR 30 -- Researchers detail in "Rational approach to select small peptide molecular probes labeled with fluorescent cyanine dyes for in vivo optical imaging," new data in Molecular Imaging. According to the authors of recent research from St. Louis, Missouri, "We demonstrate that the structure of carbocyanine dyes, which are commonly used to label small peptides for molecular imaging and not the bound peptide, controls the rate of extravasation from blood vessels to tissue. By examining several near-infrared (NIR) carbocyanine fluorophores, we demonstrate a quantitative correlation between the binding of a dye to albumin, a model plasma protein, and the rate of...

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