Medical News Article on Blood Research

Researchers' Work from Baptist Health South Florida Focuses on Blood Research

2012 MAY 2 -- According to the authors of recent research published in the journal BMC Medical Informatics and Decision Making, "Therapeutic drug monitoring of phenytoin by measurement of plasma concentrations is often employed to optimize clinical efficacy while avoiding adverse effects. This is most commonly accomplished by measurement of total phenytoin plasma concentrations."

"However, total phenytoin levels can be misleading in patients with factors such as low plasma albumin that alter the free (unbound) concentrations of phenytoin. Direct measurement of free phenytoin concentrations in plasma is more costly and time-consuming than...

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