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Medical News Article on Breast Cancer

Normal gene hinders breast cancer chemotherapy

2012 JUN 27 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech Week -- HOUSTON - Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective. The preclinical study led by MD Anderson scientists was published in the journal Cancer Cell.

The research, which challenges the existing paradigm, is another step closer to personalized cancer medicine for breast cancer.

"It's really important to understand the genetic defects a tumor cell has before we treat it," said lead author Guillermina Lozano, Ph.D., professor and chair of the Department of...

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