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Medical News Article on Gene Therapy

Transcription factor Lyl-1 critical in producing early T-cell progenitors

2012 JUL 23 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- A transcription factor called Lyl-1 is necessary for production of the earliest cells that can become T-cells, critical cells born in the thymus that coordinate the immune response to cancer or infections, said a consortium of researchers led by those from Baylor College of Medicine (www.bcm.edu) in a report in the journal Nature Immunology.

These earliest progenitors (called early T lineage progenitor cells) are the first cells that can be identified as being on the road to becoming T-cells, said Dr. Margaret Goodell ...

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