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Medical News Article on Systemic Sclerosis Genetics



Reports from University of Texas, Health Science Center highlight recent research in systemic sclerosis genetics



2007 SEP 10 -- Current study results from the report, "An allograft inflammatory factor 1 (AIF1) single nucleotide polymorphism (SNP) is associated with anticentromere antibody positive systemic sclerosis," have been published. In this recent study, researchers in the United States conducted a study "To identify genetic associations between allograft inflammatory factor 1 (AIF1) and systemic sclerosis (SSc), or its subsets, using a single nucleotide polymorphism (SNP) in a replicate case-control study. The frequencies of alleles and genotypes of an SNP, rs2269475, for the AIF1 gene were examined in two large independent cohorts of SSc patients (n=1015 total), and compared with...

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