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Klebsiella pneumoniae
Findings from Hippokrateion Hospital advance knowledge in Klebsiella pneumoniae
May 9th, 2008
(NewsRx.com) -- According to a study from Thessaloniki, Greece, "From November 2006 to April 2007, nine nonrepetitive isolates of Klebsiella pneumoniae with reduced susceptibility or resistance to carbapenems were recovered from clinical specimens from separate patients hospitalized in a tertiary care hospital." "The imipenem-EDTA synergy test was positive for all isolates. PCR, sequencing, and transferability experiments revealed the novel bla(VIM-12), metallo-beta-lactamase gene, which was plasmid mediated and located in a class 1 integron," wrote D. Tokatlidou and colleagues, Hippokrateion Hospital. The researchers concluded: "Pulsed-field gel electrophoresis demonstrated a single macrorestriction pattern, indicating the clonal spread of VIM-12-producing K. pneumoniae." Tokatlidou and colleagues published their study in the Journal of Clinical Microbiology (Outbreak caused by a multidrug-resistant Klebsiella pneumoniae clone carrying bla(VIM-12) in a university hospital. Journal of Clinical Microbiology, 2008;46(3):1005-1008). For more information, contact D. Sofianou, Hippokrateion Hospital, Dept. of Clinic Microbiology, Thessaloniki, Greece. Publisher contact information for the Journal of Clinical Microbiology is: American Society Microbiology, 1752 N St. NW, Washington, DC 20036-2904, USA. Keywords: Greece, Thessaloniki, Anti-Infectives, Clinical Microbiology, Drug Development, Drug Resistance, Imipenem, Klebsiella pneumoniae, Therapy, Treatment, Hippokrateion Hospital. This article was prepared by NewsRx editors from staff and other reports. Copyright 2008, NewsRx.com.
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