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Medical News Article on Combination Therapy
Research on combination therapy discussed by J.M. Neutel and co-researchers
2008 MAY 5 -- "This prospective, double-blind, parallel-group study randomized patients with moderate hypertension ( seated systolic blood pressure (SeSBP) 160-179mmHg when seated diastolic blood pressure (SeDBP) <110mmHg; or SeDBP 100-109mmHg when SeSBP <180mmHg) 3: 1:1 to treatment with irbesartan 300mg/hydrochlorothiazide ( HCTZ) 25mg combination therapy (n = 328), irbesartan 300mg monotherapy ( n = 106) or HCTZ monotherapy 25mg ( n 104). Treatment was initiated at half dose, with forced titration to full dose after two weeks followed by ten further weeks' treatment," scientists in the United States report.
"The primary efficacy variable was the mean...
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