Research from Mayo Clinic broadens understanding of HIV/AIDS co-infection
2009 JUL 13 - (NewsRx.com) -- "Pneumocystis pneumonia (PCP) is an infection of the lungs caused by the opportunistic fungal genus Pneumocystis," researchers in the United States report. "In humans, PCP is a serious and potentially life-threatening infection occurring in immunocompromised individuals, particularly those who have AIDS, or following immune suppression from malignancy, organ transplantation, or therapies for inflammatory diseases. Several recent studies have contributed to understanding of the biology and pathogenesis of the organism yielding new diagnostic approaches and therapeutic targets," wrote B.J. Krajicek and colleagues, Mayo Clinic. The researchers concluded: "Although trimethoprim-sulfamethoxazole remains the mainstay of prophylaxis and treatment, ongoing concerns for emerging Pneumacystis resistance supports the continuing investigation for novel therapeutic agents.." Krajicek and colleagues published their study in Clinics in Chest Medicine (Pneumocystis Pneumonia: Current Concepts in Pathogenesis, Diagnosis, and Treatment. Clinics in Chest Medicine, 2009;30(2):265+). For additional information, contact A.H. Limper, Mayo Clinic, Division Pulmology & Critical Care Medical, 200 1st St. SW, Rochester, MN 55905, USA. Publisher contact information for the journal Clinics in Chest Medicine is: W B Saunders Co-Elsevier Inc., 1600 John F Kennedy Boulevard, Ste. 1800, Philadelphia, PA 19103-2899, USA. Keywords: United States, Rochester, HIV/AIDS Co-Infection, AIDS, Acquired Immunodeficiency Syndrome, HIV, Human Immunodeficiency Virus Fungal Infection, Immunology, Infectious Disease, Inflammation, Opportunistic Infections, Pneumocystis Pneumonia, Pneumonia, Pulmonology, Therapy, Transplantation, Treatment, Virology, Mayo Clinic. This article was prepared by AIDS Weekly editors from staff and other reports. Copyright 2009, AIDS Weekly via NewsRx.com.
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