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Hematologic Disease



Avalon Pharmaceuticals Announces Positive Interim Results for AVN944 Phase I Trial



July 5th, 2007

Avalon Pharmaceuticals, Inc. (NASDAQ:AVRX), announced continued positive interim results from its Phase I study of AVN944, for the treatment of hematologic malignancies in elderly and refractory patients. Interim data indicate AVN944 is well tolerated, has dose-dependent pharmacokinetics, induces biomarkers of programmed cell death in cancer cells from patients, and demonstrates stabilized disease in almost half of the patients after one-month of treatment.

"We continue to be encouraged by the positive interim results from the AVN944 trial," stated Michael Hamilton, M.D., Avalon Pharmaceuticals' Chief Medical Officer. "We have observed important indications of biological...


Source: Blood Weekly (2007-07-05)