Research from H. Elmahy and co-researchers yields new findings on lymphoma
2008 JAN 17 -- According to recent research from Wigan, the United Kingdom, "The simultaneous occurrence of Hodgkin lymphoma with a variety of B-cell Non-Hodgkin lymphomas (composite lymphoma) has been described. We report the first case of composite Hodgkin lymphoma and splenic marginal zone lymphoma occurring simultaneously in the same lymph node of a 64-year-old man who presented with cervical and axillary lymphadenopathy and massive splenomegaly." "He had a peripheral blood lymphocytosis and a bone marrow infiltrated by small lymphocytes. However, cervical lymph node biopsy showed classic Hodgkin lymphoma. His splenomegaly showed only a partial response to six cycles of ABVD chemotherapy so he underwent splenectomy with biopsy of remaining nodes. Histology of the spleen and nodes showed splenic marginal zone lymphoma," wrote H. Elmahy and colleagues. The researchers concluded: "Review of the original biopsy confirmed the presence of both diseases in the original lymph node." Elmahy and colleagues published their study in International Journal of Laboratory Hematology (Composite splenic marginal zone lymphoma and classic Hodgkin lymphoma - an unusual combination. International Journal of Laboratory Hematology, 2007;29(6):461-463). For additional information, contact H. Elmahy, Royal Albert Edward Infirmary A&E, Wigan WN1 2NN, Lancs, UK. Publisher contact information for the International Journal of Laboratory Hematology is: Blackwell Publishing, 9600 Garsington Rd., Oxford OX4 2DQ, Oxon, England. Keywords: United Kingdom, Wigan, Hematology, Lymphadenopathy, Lymphocytosis, Non-Hodgkin Lymphoma, Oncology, Splenomegaly. This article was prepared by Blood Weekly editors from staff and other reports. Copyright 2008, Blood Weekly via NewsRx.com.
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