Research from Chonnam National University yields new findings on ring cell cancer
2009 JUL 14 - (NewsRx.com) -- "Signet ring cell carcinoma is a very rare subtype of adenocarcinoma of the urinary bladder. Urine cytology is a useful method for screening and follow-up of urinary bladder carcinoma," researchers in South Korea report. "A 43-year-old woman was referred for evaluation of painless hematuria. Laboratory evaluation showed anemia, hematuria and elevated tumor marker levels. Pelvic computed tomography (CT) demonstrated diffuse wall thickening, and the chest CT suggested metastatic lesions in the lung and hepatic dome. Abdominal CT, esophagogastroduodenoscopy and colonoscopy revealed no evidence of malignancy in the gastrointestinal tract. Cystoscopy revealed very large masses in the anterior and posterior wall of the bladder. Bladder washings, urine cytology and biopsy demonstrated characteristic signet ring cells without foci of urothelial carcinoma or other lesions. Three months later, ascitic fluid was obtained, the results showed signet ring cells identical to those seen in the urine specimen," wrote S.S. Kim and colleagues, Chonnam National University. The researchers concluded: "Signet ring tell carcinoma of the urinary bladder call be diagnosed by urinary cytology, and confirmed by cytoscopic biopsy. (Acta Cytol 2009;53: 309-312)." Kim and colleagues published their study in Acta Cytologica (Cytologic Features of Primary Signet Ring Cell Carcinoma of the Bladder A Case Report. Acta Cytologica, 2009;53(3):309-312). For additional information, contact C. Choi, Chonnam National University, Dept. of Pathology, Hwasun Hospital, 160 Ilsim Ri, Hwasun Gun 519809, Chonnam, South Korea. Publisher contact information for the journal Acta Cytologica is: Science Printers & Publ Inc., PO Drawer 12425 8342 Olive Blvd., St. Louis, MO 63132, USA. Keywords: South Korea, Adenocarcinoma, Bladder Cancer, Bladder Carcinoma, Colonoscopy, Cytology, Gastroenterology, Hematuria, Nephrology, Oncology, Ring Cell Cancer, Ring Cell Carcinoma, Signet-Ring Cell Carcinoma, Chonnam National University. This article was prepared by Cancer Weekly editors from staff and other reports. Copyright 2009, Cancer Weekly via NewsRx.com.
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