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Cancer



Scientists Discover New Role for MicroRNAs in Stopping Tumor Cell Growth



July 6th, 2007

Scientists at Cold Spring Harbor Laboratory (CSHL), Howard Hughes Medical Institute (HHMI), and Applied Biosystems (NYSE: ABI), an Applera Corporation business, have discovered that a family of small RNA molecules known as microRNAs (miRNAs) are components in a well-studied tumor suppressor network, the p53 pathway, that stops the growth of tumor cells in mice. This tumor suppressor capability represents a newly discovered function for miRNAs. The finding may also suggest new approaches for treating cancers. The results of the team's two-year collaboration will be published in the June 28th issue of the journal Nature. Other co-authors were from Stony Brook University and Rosetta...


Source: Genomics & Genetics Weekly (2007-07-06)