New cardiology study findings have been published by H. Okura and colleagues
2009 JUL 12 - (NewsRx.com) -- According to recent research from Kurashiki, Japan, "Although left ventricular diastolic function has been shown to deteriorate with advancing age, its gender-specific change is unknown. The aim of this study was to investigate age- and gender-specific changes in tissue Doppler-derived left ventricular diastolic index, E'." "A total of 1333 healthy individual without known heart disease or hypertension (mean age, 55 years: range, 10 to 89) were enrolled and studied. Peak early mitral annular velocity (E') and peak late mitral annular velocity (A') were recorded and measured. As an index of the left ventricular relaxation, E' was used. As all index of the left ventricular filling pressure, E/E' was calculated. Although Systolic indices poorly correlated with age, diastolic indices correlated well with age. Among those aged 30 to 39 and 40 to 49 years, E' was significantly lower in males than in females. In subjects aged 50 to 59 and 60 to 69 years. E' was similar in both genders. Among those aged 70 to 79 and 80 to 89),cars, F was significantly lower in females than in males. Predictors of the lowest quartile of E' among subjects aged >50 years were age (p <0.0001; chi(2)=66.11 odds ratio. 1.08; 95% CI, 1.058 to 1.097) and female gender (P=0.001 chi(2)=9.23 odds ratio, 1.68. 95% CI, 1.202 to 2.343). Age-related changes in diastolic indices Were (Tender specific. In the elderly population, diastolic function deteriorated more significantly in the female gender than in the male gender," wrote H. Okura and colleagues. The researchers concluded: "These results may explain the relatively higher incidence in elderly females among patients with diastolic heart failure and higher cardiovascular mortality in the female gender. (Circ Cardiovasc Imaging. 2009,2:41-46.)'." Okura and colleagues published their study in Circulation - Cardiovascular Imaging (Age- and Gender-Specific Changes in the Left Ventricular Relaxation A Doppler Echocardiographic Study in Healthy Individuals. Circulation - Cardiovascular Imaging, 2009;2(1):41-46). For additional information, contact H. Okura, Kawasaki Med University, Division Cardiology, 577 Matsushima, Kurashiki, Okayama 7010192, Japan. Publisher contact information for the journal Circulation - Cardiovascular Imaging is: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA. Keywords: Japan, Kurashiki, Aging, Cardiography, Cardiology, Cardiovascular, Echocardiography, Gender Health, Gender Medicine, Heart Disease, Hypertension, Women's Health. This article was prepared by Heart Disease Weekly editors from staff and other reports. Copyright 2009, Heart Disease Weekly via NewsRx.com.
|
