Research data from Loyola University update understanding of anesthesia
2009 JUL 13 - (NewsRx.com) -- "A multicenter study (BREATHE I - Entellus Medical, Inc.) Was performed to assess the safety and outcomes of a new, less invasive system that uses direct endoscopic visualization to facilitate balloon dilation of the maxillary sinus ostia and ethmoid infundibulum. General anesthesia was avoided in most subjects to assess feasibility of performing transantral ostial dilatation in an office setting," scientists in the United States report. "Subjects with chronic rhinosinusitis of the maxillary sinuses alone or maxillary and anterior ethmoid sinuses underwent baseline evaluation including CT imaging and symptom assessment using the Sino-Nasal Outcome Test (SNOT 20). underwent transantral balloon dilation and follow-up evaluation at 1 week, 3 months, and 6 months post-procedure. Thirty subjects were treated at three centers. Fifty-five of 58 maxillary ostia were successfully treated for a procedural completion rate of 94.8%. Ninety-seven percent of the procedures were completed under local anesthesia With or Without minimal intravenous sedation. There were no device-related serious adverse events or unanticipated adverse device effects. The mean overall SNOT 20 score at baseline zoos 2.9 +/- 1.0. Mean overall SNOT 20 scores at 1-week, 3-month, and 6-month follow-up were 0.8 +/- 0.8, 0.7 +/- 0.8, and 0.8 +/- 0.9 respectively. Patency at 3-months as confirmed by CT imaging was 95.8%," wrote J. Stankiewicz and colleagues, Loyola University. The researchers concluded: "These results indicate that transantral balloon dilation of the ostiomeatal complex under local anesthesia appears to be a safe technique for managing isolated maxillary or maxillary and anterior ethmoid sinusitis and call potentially be performed safety in an office setting. (Am J Rhinol Allergy 23, 321-327, 2009; doi: 10.2500/ajra.2009.23.3274)." Stankiewicz and colleagues published their study in American Journal of Rhinology & Allergy (Transantral, endoscopically guided balloon dilatation of the ostiomeatal complex for chronic rhinosinusitis under local anesthesia. American Journal of Rhinology & Allergy, 2009;23(3):321-327). For additional information, contact J. Stankiewicz, Loyola University, Medical Center, Dept. of Otolaryngology, 2160 S 1st Avenue, Maywood, IL 60153, USA. The publisher's contact information for the American Journal of Rhinology & Allergy is: Ocean Side Publications Inc., 95 Pitman St., Providence, RI 02906, USA. Keywords: United States, Maywood, Allergies, Allergy Medicine, Anesthesia, Local Anesthesia, Pain Medicine, Rhinology, Loyola University. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.
|
