Pain & Central Nervous System Week

New data from Duke University illuminate research in anesthesiology

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"Three-dimensional geometric computer-based models were created representing two 18-gauge, insulated Tuohy needles: (1) with an exposed metal tip and (2) with an insulated tip. The models were projected in simulated human tissue. Using finite element methodology, distributions of current-density were calculated. Voltages in die modeled medium were calculated, and activation patterns of a model nerve fiber around the tip of each needle were estimated using the activating function. Maximum current density on the exposed-tip needle occurred along the edge of the distal tip; the distal edge was 1.7 times larger than the side edges and 3.5 times larger than the proximal edge. Conversely, maximum current density occurred along the proximal edge of the insulated-tip Tuohy opening; the proximal edge was 1.9 times larger than the side edges of the opening and 3.5 times larger than the distal edge of the opening. Voltages generated by the exposed-tip needle were larger and had a wider spatial distribution than that of the insulated-tip needle, which restricted to the area immediately adjacent to the opening. Different changes in threshold were predicted to excite a nerve fiber as the needles were rotated or advanced toward the modeled nerve. The needles displayed different asymmetric distributions of current density and positional effects on threshold," wrote M.B. Cantrell and colleagues, Duke University.

The researchers concluded: "If this analysis is validated clinically, it may prove useful in testing stimulating needles before clinical application.."

Cantrell and colleagues published their study in Anesthesiology (Computer-based Finite Element Modeling of Insulated Tuohy Needles Used in Regional Anesthesia. Anesthesiology, 2009;110(6):1229-1234).

For additional information, contact S.M. Klein, Duke University, Medical Center, Dept. of Anesthesiology, Box 3094, Durham, NC 27710, USA.

The publisher of the journal Anesthesiology can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA.

Keywords: United States, Box, Life Sciences, Pain Medicine, Anesthesia, Anesthesiology, Duke University.

This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.