Studies from University of Miami have provided new data on stem cell research
2009 JUL 13 - (NewsRx.com) -- According to recent research from the United States, "Mesenchymal stem cells (MSCs) are a heterogeneous population of stem/progenitor cells with pluripotent capacity to differentiate into mesodermal and non-mesodermal cell lineages, including osteocytes, adipocytes, chondrocytes, myocytes, cardiomyocytes, fibroblasts, myofibroblasts, epithelial cells, and neurons. MSCs reside primarily in the bone marrow, but also exist in other sites such as adipose tissue, peripheral blood, cord blood, liver, and fetal tissues." "When stimulated by specific signals, these cells can be released from their niche in the bone marrow into circulation and recruited to the target tissues where they undergo in situ differentiation and contribute to tissue regeneration and homeostasis. Several characteristics of MSCs, such as the potential to differentiate into multiple lineages and the ability to be expanded ex vivo while retaining their original lineage differentiation commitment, make these cells very interesting targets for potential therapeutic use in regenerative medicine and tissue engineering. The feasibility for transplantation of primary or engineered MSCs as cell-based therapy has been demonstrated," wrote Z.J. Liu and colleagues, University of Miami. The researchers concluded: "In this review, we summarize the current knowledge on the signals that control trafficking and differentiation of MSCs. J. Cell. Biochem. 106: 984-991, 2009." Liu and colleagues published their study in the Journal of Cellular Biochemistry (Trafficking and Differentiation of Mesenchymal Stem Cells. Journal of Cellular Biochemistry, 2009;106(6):984-991). For additional information, contact O.C. Velazquez, University of Miami, Division Vascular & Endovasc Surgery, DeWitt Daughtry Family Dept. of Surgery, Jackson Mem Med Center, Leonard M Miller School Medical, 1611 NW 12th Avenue, E Tower 3016, Miami, FL 33136, USA. Publisher contact information for the Journal of Cellular Biochemistry is: Wiley-Liss, Division John Wiley & Sons Inc., 111 River St., Hoboken, NJ 07030, USA. Keywords: United States, Tower, Blood Transfusion, Bone Marrow, Cardiology, Cardiomyocyte, Cell Differentiation, Cellular Biochemistry, Circulation, Cord Blood, Medical Device, Progenitor Cell, Stem Cell Research, Transfusion Medicine, University of Miami. This article was prepared by Stem Cell Week editors from staff and other reports. Copyright 2009, Stem Cell Week via NewsRx.com.
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