Reports outline life sciences research from R. Kulkarni and colleagues
2009 JUL 23 - (NewsRx.com) -- According to recent research from the United States, "Electrical impedance tomography is being explored as a technique to detect breast cancer, exploiting the differences in admittivity between normal tissue and tumors. In this paper, the geometry is modeled as an infinite half space under a hand-held probe." "A forward solution and a reconstruction algorithm for this geometry were developed previously by Mueller et al (1999 IEEE Trans. Biomed. Eng. 46 1379). In this paper, we present a different approach which uses the decomposition of the forward solution into its Fourier components to obtain the forward solution and the reconstructions. The two approaches are compared in terms of the forward solutions and the reconstructions of experimental tank data. We also introduce a two-layered model to incorporate the presence of the skin that surrounds the body area being imaged. We demonstrate an improvement in the reconstruction of a target in a layered medium using this layered model with finite difference simulated data. We then extend the application of our layered model to human subject data and estimate the skin and the tissue admittivities for data collected on the human abdomen using an ultrasound-like hand-held EIT probe," wrote R. Kulkarni and colleagues. The researchers concluded: "Lastly, we show that for this set of human subject data, the layered model yields an improvement in predicting the measured voltages of around 81% for the lowest temporal frequency (3 kHz) and around 61% for the highest temporal frequency (1 MHz) applied when compared to the homogeneous model." Kulkarni and colleagues published their study in Physiological Measurement (A two-layered forward model of tissue for electrical impedance tomography. Physiological Measurement, 2009;30(6):S19-S34). For additional information, contact R. Kulkarni, Rensselaer Polytechnic Institute, Dept. of Electrical Computational & Systems Engineering, Troy, NY 12180, USA. Publisher contact information for the journal Physiological Measurement is: IOP Publishing Ltd., Dirac House, Temple Back, Bristol BS1 6BE, England. Keywords: United States, Troy, Life Sciences, Breast Cancer, Breast Carcinoma, Oncology, Women's Health, Physiology. This article was prepared by World Disease Weekly editors from staff and other reports. Copyright 2009, World Disease Weekly via NewsRx.com.
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