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Data from Central Institute for Animal Disease Control provide new insights into bird flu vaccines



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2008 FEB 12 -- Researchers detail in 'Variable effect of vaccination against highly pathogenic avian influenza (H7N7) virus on disease and transmission in pheasants and teals,' new data in bird flu. "Highly pathogenic avian influenza viruses can affect many bird species, with disease symptoms ranging from severe morbidity and high mortality to mild transient illness. Much is known about infections in chickens, but for other captive birds the relations between disease symptoms, excretion patterns, and transmission, as well as the effect of vaccination on these relations are not clear," researchers in Netherlands report.

"We report results from experimental transmission studies with a highly pathogenic H7N7 virus and two commonly kept bird species (ringed teals and golden pheasants). The results show that depending on the host species the virus can spread in unvaccinated birds with or without disease symptoms. Vaccination reduces disease symptoms markedly, but need not always reduce virus transmission," wrote der Goot J.A. van and colleagues, Central Institute for Animal Disease Control.

The researchers concluded: "We discuss the implications for the control of highly pathogenic avian influenza."

van and colleagues published their study in Vaccine (Variable effect of vaccination against highly pathogenic avian influenza (H7N7) virus on disease and transmission in pheasants and teals. Vaccine, 2007;25(49):8318-25).

For additional information, contact J.A. van der Goot, Central Institute for Animal Disease Control Lelystad, Virology Department, Houtribweg 39, 8221 RA Lelystad, Netherlands.

Publisher contact information for the journal Vaccine is: Elsevier Science Ltd., the Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England.

Keywords: Netherlands, Bird Flu Vaccines, Avian Flu, Avian Influenza, Avian Influenza Virus, Biotechnology, Bird Flu, Vaccines, Viral Research, Virology.

This article was prepared by World Disease Weekly editors from staff and other reports. Copyright 2008, World Disease Weekly via NewsRx.com.