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Researchers from Henri Mondor Hospital, Department of Dermatology describe findings in acne vulgaris therapy



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This article was published in Biotech Business Week, which you can subscribe to online.

2007 NOV 19 -- New research, 'Acne on pigmented skin,' is the subject of a report. "Acne on pigmented skin occurs in Africans and their descendants, as well as in patients with a skin phototype above IV. Acne is common in Africans and is often the primary reason for consulting a dermatologist," investigators in Creteil, France report.

"Acne on pigmented skin is principally inflammatory acne. The sequelae in terms of pigmentation are often the main reason for consulting a dermatologist, and take precedence over the acne itself. Research is needed into cosmetic acne and steroid-induced dermatitis, which are common in users of skin bleaching products. The treatment for acne in pigmented skin involves the same medicines as used in acne in white skin. Of the available topical treatments, benzoyl peroxide is particularly effective for the inflammatory component. Retinoids act on both the retentional and inflammatory components of acne and have skin bleaching properties. Tetracyclines are essential on initiation of treatment, regardless of severity. They prevent an inflammatory episode at the onset of acne and rapidly improve the inflammatory component. Minocycline should not be prescribed in African patients. Fatal cases of hypersensitivity have been described, with a particular frequency in this population. Doxycycline is effective, but has photosensitizing properties. Lymecycline is well tolerated. Isotretinoin is indicated for nodular acne. The same precautions for use should be followed as in all cases of acne. The skin bleaching effects are considerable. Photoprotection should generally be imposed, but, in patients with black skin, photoprotective agents are often not applied," wrote F. Poli and colleagues, Henri Mondor Hospital, Department of Dermatology.

The researchers concluded: "The administration of a cosmetic containing a skin bleaching agent combined with a photoprotective agent for application in the morning, instead of hydrating cream, is acceptable to patients, improves compliance, and is effective."

Poli and colleagues published their study in International Journal of Dermatology (Acne on pigmented skin. International Journal of Dermatology, 2007;46 Suppl 1():39-41).

For additional information, contact F. Poli, Henri Mondor Hospital, Dept. of Dermatology, Creteil, France.

The publisher of the International Journal of Dermatology can be contacted at: Blackwell Publishing Ltd., 9600 Garsington Rd., Oxford OX4 2DG, Oxon, England.

Keywords: France, Creteil, Acne Vulgaris Therapy, Acne Vulgaris, Dermatology, Therapy, Treatment.

This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2007, Biotech Business Week via NewsRx.com.