Study findings from Monash University, Skin and Cancer Foundation provide new insights into angiogenesis
2007 NOV 12 -- New research, 'The management of postacne scarring,' is the subject of a report. "Therapeutic intervention for postacne scarring has historically been limited by the considerable morbidity of most treatments for only marginal disease improvement. Within the past decade, however, a greater understanding of the pathogenesis of acne scarring has led to the development of techniques that offer more favorable risk-benefit profiles The aims of this article are to highlight a number of newer techniques and to assign their appropriateness to particular grades of acne scarring Current modalities are discussed as they relate to disease process and specific acne scar types," scientists writing in the journal Dermatologic Surgery report. "Techniques are presented in order of most effectual therapeutic interventions for defined grades of acne scarring. Acne scarring grades have been described previously in terms of disease load, severity, and lesion morphologies A comprehensive discussion of updated therapeutic techniques and their biologic rationales in the treatment of acne scarring is presented. These include targeted interventions of inflammatory and postinflammatory processes, angiogenesis, immunologic processes, dermal and subcutaneous fibrosis, hypertrophy, and keloid scarring A requirement for developing successful treatments for postacne scarring is a greater understanding of its pathogenesis, variability among afflicted individuals, and the inflammatory mediators and immunology of the scarring process," wrote G.J. Goodman and colleagues, Monash University, Skin and Cancer Foundation. The researchers concluded: "Many innovative techniques introduced in the past decade attempt to counteract these pathologic processes while keeping the procedural and postoperative risks to a minimum." Goodman and colleagues published their study in Dermatologic Surgery (The management of postacne scarring. Dermatologic Surgery, 2007;33(10):1175-88). Additional information can be obtained by contacting G.J. Goodman, Victoria, Skin and Cancer Foundation of Victoria and Monash University Dept. of Community Medicine, Australia. The publisher of the journal Dermatologic Surgery can be contacted at: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Australia, Acne Vulgaris, Angiogenesis, Oncology, Surgery, Therapy, Treatment, Tumor Vascularization. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2007, Biotech Business Week via NewsRx.com.
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