Study findings from Ajou University broaden understanding of cancer therapy
2009 JUL 20 - (NewsRx.com) -- A report, 'Altered urinary polyamine patterns of cancer patients under acupuncture therapy,' is newly published data in Amino Acids. "The reduction of elevated polyamine (PA) levels in biological fluids of cancer patients were known to be correlated with remission following diverse therapeutic treatments. In this study, altered urinary PA levels from three different cancer cases were monitored at different intervals during the long-term weekday acupuncture treatments," researchers in Suwon, Korea report. "Nine urinary PA levels from 16 normal and three cancer patients with different types were measured by gas chromatography-mass spectrometry in selected ion monitoring mode as N-ethoxycarbonyl-N-pentafluoropropionyl derivatives. Their levels measured at three follow-up stages for each patient were then normalized to the corresponding normal group means and plotted into star symbol patterns. Large alterations of PA levels were observed for each patient. Each normalized concentration displayed elevation of the PA levels in multiples (0.0-57.7) of the respective normal mean values," wrote M.J. Paik and colleagues, Ajou University. The researchers concluded: "The normalized PA values were transformed into distorted star patterns which were characteristic of each follow-up stage and of cancer type." Paik and colleagues published their study in Amino Acids (Altered urinary polyamine patterns of cancer patients under acupuncture therapy. Amino Acids, 2009;37(2):407-13). For additional information, contact M.J. Paik, Metabolomic Analysis Laboratory, Institute for Neuroregeneration and Stem Cell Research, School of Medicine, Ajou University, Suwon 443-721, Republic of Korea. Publisher contact information for the journal Amino Acids is: Springer, 233 Spring Street, New York, NY 10013, USA. Keywords: Korea, Suwon, Cancer Therapy, Acupuncture Therapy, Amino Acids, Cancer, Chromatography, Diagnosis, Diagnostics, Drugs, Mass Spectrometry, Oncology, Pharmaceuticals, Treatment. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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