New polyps study results reported from I. Samarasam et al
2009 JUL 13 - (NewsRx.com) -- New research, 'Gastric fundic gland polyps: a clinico-pathological study from North West Tasmania,' is the subject of a report. "Fundic gland polyps (FGPs) of the stomach were originally described in association with familial polyposis syndromes. It is now known that the majority of these polyps occur in the sporadic setting and are incidentally seen in up to 1.9% of routine upper gastrointestinal endoscopes," investigators in Australia report. "The aim of this study was to look at the clinico-pathological features of the FGPs and to analyse their relationship to Helicobacter pylori infection, proton pump inhibitor treatment, colonic polyps and malignancy. A search of the histopathology records for a period of 10 years from 1997 to 2006 identified 120 patients with a histologically confirmed diagnosis of FGPs. The clinical history, upper gastrointestinal endoscopy findings, histopathology and colonoscopy findings were recorded from the medical records and analysed. FGPs were seen in 3.2% of patients undergoing routine upper gastrointestinal endoscopes. There was a definite association with long-term proton pump inhibitor treatment. There was a strikingly low incidence of H. pylori infection in the study population. Although there was no dysplasia or malignancy in any of these polyps, one patient had concomitant adenocarcinoma of the stomach. In the subgroup of patients who also had colonoscopy during the study period, 19% had associated colonic polyps and 6% had associated colonic malignancies. Every new patient diagnosed with FGPs should have a thorough clinico-pathological study to see if the polyps are part of a sporadic or syndromic setting," wrote I. Samarasam and colleagues, . The researchers concluded: "A long-term follow-up study of patients with FGPs and its association with colonic polyps may be warranted." Samarasam and colleagues published their study in ANZ Journal of Surgery (Gastric fundic gland polyps: a clinico-pathological study from North West Tasmania. ANZ Journal of Surgery, 2009;79(6):467-70). For additional information, contact I. Samarasam, Mersey Hospital, Dept. of Surgery, Latrobe, Tasmania, Australia. The publisher of the ANZ Journal of Surgery can be contacted at: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Australia, Adenomatous Polyposis Coli, Colonic Polyps, Colonoscopy, Endoscopy, Gastroenterology, Gastrointestinal Endoscopy, Histopathology, Pathology, Surgery, Therapy, Treatment. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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