New findings from A.V. Maker and co-authors in the area of pancreatic cancer published
2009 JUN 22 - (NewsRx.com) -- "Earlier detection of pancreatic cancer may help identify patients for whom surgical intervention could provide cure or prolong life. In this article, we report the occurrence of breast cancer, melanoma, squamous cell carcinoma of the alveolar ridge, colon cancer, a desmoid tumor of the abdominal wall, and pancreatic adenocarcinoma in a 65-year-old woman," scientists writing in the Journal of Gastrointestinal Surgery report. "She was identified as having the familial atypical multiple mole melanoma-pancreatic cancer syndrome (FAMMM-PC) with a germline p16 mutation at amino acid position 15. Patients with this syndrome traditionally present with multiple nevi and melanoma, and a subset also present with other cancers, including pancreatic cancer; however, no FAMMM-PC patient has yet been described with this constellation of cancers, including squamous cell carcinoma of the alveolar ridge and a desmoid tumor," wrote A.V. Maker and colleagues. The researchers concluded: "Recognition of the tumors this population of patients is susceptible to developing and their genetic associations can help guide the surgeon in screening, surveillance, and eventually prevention of many of these cancers." Maker and colleagues published their study in the Journal of Gastrointestinal Surgery (Novel Presentation of a Familial Pancreatic Cancer Syndrome. Journal of Gastrointestinal Surgery, 2009;13(6):1151-1154). Additional information can be obtained by contacting A.V. Maker, 303 E 60th St. 28-H, New York City, NY 10022, USA. The publisher of the Journal of Gastrointestinal Surgery can be contacted at: Springer, 233 Spring St., New York, NY 10013, USA. Keywords: United States, New York, Adenocarcinoma, Aggressive Fibromatosis, Breast Cancer, Breast Carcinoma, Colon Cancer, Colon Carcinoma, Gastroenterology, Gastrointestinal Surgery, Melanoma, Oncology, Pancreas, Pancreatic Cancer, Pancreatic Carcinoma, Pancreatic Neoplasms, Squamous Cell Carcinoma, Women's Health. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2009, Clinical Oncology Week via NewsRx.com.
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