Researchers at University of Verona have published new data on fabry disease
2009 JUL 20 - (NewsRx.com) -- According to recent research from Verona, Italy, "A 29-year-old white woman with a family history of Fabry disease was referred to a nephrology clinic with hypertension and nephropathy. Her renal function was below normal (serum creatinine level 141 mu mol/l; estimated glomerular filtration rate 41 ml/min/1.73 m(2)) with no proteinuria or albuminuria. Investigations." "Medical history, physical examination, leukocyte alpha-galactosidase a assay, laboratory tests (for antinuclear antibodies, antineutrophil cytoplasmic antibodies, lupus anticoagulant, anticardiolipin antibodies, complement and cryoglobulin), ophthalmological examination, echocardiography, brain magnetic resonance angiography, renal ultrasonography, renal color echo-doppler scan, renal magnetic resonance angiography, renal angiography and renal biopsy. Diagnosis. Diffuse sclero-atrophic renal tissue changes and widespread renal arterio-arteriolosclerotic changes secondary to Fabry disease. Treatment," wrote C. Abaterusso and colleagues, University of Verona. The researchers concluded: "Angiotensin-converting-enzyme inhibitors and maintenance treatment with agalsidase-beta, 1 mg/kg body weight, every 2 weeks." Abaterusso and colleagues published their study in Nature Reviews Nephrology (Unusual renal presentation of Fabry disease in a female patient. Nature Reviews Nephrology, 2009;5(6):349-354). For additional information, contact C. Abaterusso, University of Verona, Osped Maggiore, Division Nephrology, Dept. of Biomedical & Surgery Science, Ple Stefani 1, I-37126 Verona, Italy. Publisher contact information for the journal Nature Reviews Nephrology is: Nature Publishing Group, 75 Varick St., 9TH Flr, New York, NY 10013-1917, USA. Keywords: Italy, Verona, Albuminuria, Antinuclear Antibodies, Enzyme Research, Fabry Disease, Galactosidase, Hypertension, Immunology, Kidney, Lupus, Nephrology, Nephropathy, Neurology, Proteinuria, Renal Function, University of Verona. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.
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