Allergy Medicine


Researchers from Finnish Institute of Occupational Health report details of new studies and findings in the area of allergic reactions



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2007 NOV 20 -- Current study results from the report, 'Methacrylate and acrylate allergy in dental personnel,' have been published. According to a study from Helsinki, Finland, "Methacrylates are important allergens in dentistry The study aimed to analyse patch test reactivity to 36 acrylic monomers in dental personnel in relation to exposure We reviewed the test files at the Finnish Institute of Occupational Health from 1994 to 2006 for allergic reactions to acrylic monomers in dental personnel and analysed the clinical records of the sensitized patients 32 patients had allergic reactions to acrylic monomers: 15 dental nurses, 9 dentists, and 8 dental technicians. The dentists and dental nurses were most commonly exposed to 2-hydroxyethyl methacrylate (2-HEMA), triethyleneglycol dimethacrylate (TREGDMA), and 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (bis-GMA). 8 dentists and 12 dental nurses were allergic to 2-HEMA."

"The remaining dentist was positive to bis-GMA and other epoxy acrylates. The remaining 3 dental nurses reacted to diethyleneglycol diacrylate (DEGDA) or triethyleneglycol diacrylate (TREGDA), but not to monofunctional and multifunctional methacrylates. Our dental technicians were mainly exposed and sensitized to methyl methacrylate (MMA) and ethyleneglycol dimethacrylate (EGDMA). 1 technician reacted only to 2-HEMA, and another to ethyl methacrylate (EMA) and ethyl acrylate (EA) 2-HEMA was the most important allergen in dentists and dental nurses, and MMA and EGDMA in dental technicians," wrote K. Aalto-Korte and colleagues, Finnish Institute of Occupational Health.

The researchers concluded: "Reactions to bis-GMA, DEGDA, TREGDA, EMA and EA were relevant in some patients."

Aalto-Korte and colleagues published their study in Contact Dermatitis (Methacrylate and acrylate allergy in dental personnel. Contact Dermatitis, 2007;57(5):324-30).

For more information, contact K. Aalto-Korte, Finnish Institute of Occupational Health, Control of Hypersensitivity Diseases, Helsinki, Finland.

Publisher contact information for the journal Contact Dermatitis is: Blackwell Munksgaard, 35 Norre Sogade, PO Box 2148, DK-1016 Copenhagen, Denmark.

Keywords: Finland, Helsinki, Allergic Reactions, Allergies, Allergy Medicine, Contact Dermatitis, Dermatology, Occupational Health.

This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2007, Life Science Weekly via NewsRx.com.