Reports from M. Citirik and colleagues advance knowledge in Alport syndrome
2007 NOV 6 -- ": To report a case of Alport's syndrome and to present electronmicroscopic examination findings of the anterior lens capsule of this patient. A 21-year-old man was referred for low visual acuity and retinal pigment epithelial changes in the left eye. The patient and his relatives underwent detailed ophthalmological examination, including electrophysiological testing," investigators in Ankara, Turkey report. "The patient also underwent electronmicroscopic examination of the anterior lens capsule. His visual acuity was 6/18 OD and 6/15 OS. Anterior lenticonus and subcapsular opacities were observed in the left eye. Cataract extraction by phacoemulsification with intraocular lens implantation was performed for his poor visual performance. During the capsulorhexis, the remarkably thin and fragile anterior capsule was noted and removed. Ultrastructural analysis of the anterior lens capsule showed a thinner central zone compared with the periphery. Concludions: The course of Alport's syndrome can be ameliorated by early diagnosis. Therefore, the ophthalmological examination of a patient with anterior lenticonus must be combined with a detailed medical evaluation," wrote M. Citirik and colleagues. The researchers concluded: "Ultrastructural analysis of the lens capsule can support the diagnosis of Alport's syndrome." Citirik and colleagues published their study in Clinical and Experimental Optometry (Electron microscopic examination of the anterior lens capsule in a case of Alport's syndrome. Clinical and Experimental Optometry, 2007;90(5):367-370). For additional information, contact M. Citirik, SB Ankara Ulcanlar Eye Hospital, Ankara, Turkey. The publisher of the journal Clinical and Experimental Optometry can be contacted at: Blackwell Publishing, 9600 Garsington Rd., Oxford OX4 2DQ, Oxon, England. Keywords: Turkey, Ankara, Alport Syndrome, Hereditary Nephritis. This article was prepared by Medical Imaging Law Week editors from staff and other reports. Copyright 2007, Medical Imaging Law Week via NewsRx.com.
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