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Androgenetic Alopecia


Reports on atherosclerosis findings from Mustafa Kemal University, Medical Department provide new insights



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This article was published in Pain & Central Nervous System Week, which you can subscribe to online.

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2009 JUL 13 - (NewsRx.com) -- According to recent research published in the Journal of the European Academy of Dermatology and Venereology, "Several studies have demonstrated the presence of an association between androgenetic alopecia (AGA) and cardiovascular disease. The aim of this study was to evaluate subclinical atherosclerosis in patients with AGA and healthy controls by the incorporation of carotid intima-media thickness (IMT) and high-sensitive C-reactive protein (hs-CRP) along with echocardiography (ECHO) and exercise electrocardiography (ExECG)."

"We performed a case-control study in 50 male patients with AGA and 31 age-matched healthy male controls with normal hair status. Both the AGA patients and controls with a history of diabetes mellitus, cigarette smoking, hypertension, cardiovascular or cerebrovascular disease, and renal failure were excluded. AGA was classified according to the Hamilton-Norwood scale. Serum lipids, serum hs-CRP, total testosterone, and dehydroepiandrosterone sulphate were examined in all study subjects. Carotid ultrasonography was used to measure the IMT of the common carotid arteries (CCA). ECHO and ExECG were performed in all subjects. IMT of the CCA was found to be significantly higher in patients with severe vertex pattern AGA when compared to patients with other patterns of AGA and healthy controls (P < 0.05). Hs-CRP in patients with any group of AGA was not significantly different from those healthy controls (P > 0.05). ECHO showed that cardiac structural and functional measures were in normal ranges. ExECG was also normal in all subjects. Severe vertex pattern AGA should be considered to have an increased risk of subclinical atherosclerosis," wrote A.C. Dogramaci and colleagues, Mustafa Kemal University, Medical Department.

The researchers concluded: "For this reason, CCA IMT measurement can be recommended as a non-invasive and early diagnostic method. None declared."

Dogramaci and colleagues published their study in the Journal of the European Academy of Dermatology and Venereology (Is androgenetic alopecia a risk for atherosclerosis' Journal of the European Academy of Dermatology and Venereology, 2009;23(6):673-677).

For additional information, contact A.C. Dogramaci, Mustafa Kemal University, Faculty Medical, Dept. of Dermatology, Antakya, Turkey.

The publisher's contact information for the Journal of the European Academy of Dermatology and Venereology is: Wiley-Blackwell Publishing, Inc., Commerce Place, 350 Main St., Malden 02148, MA, USA.

Keywords: Turkey, Antakya, Alopecia, Angiology, Atherosclerosis, Biotechnology, C Reactive Protein, Cardiography, Cardiology, Cardiovascular Disease, Cerebrovascular Disease, Clinical Trial Research, Dermatology, Diabetes, Diabetes Mellitus, Drugs, Echocardiography, Endocrinology, Genetics, Hypertension, Kidney, Nephrology, Pharmaceuticals, Proteomics, Renal Failure, Testosterone, Therapy, Treatment, Venereology, Mustafa Kemal University, Medical Department.

This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.

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