Studies from F.S. Aslani and co-researchers update current data on alopecia genetics
2009 JUN 30 - (NewsRx.com) -- New research, 'Hair counts in scalp biopsy of males and females with androgenetic alopecia compared with normal subjects,' is the subject of a report. "Hair counts were studied in scalp biopsy specimens of androgenetic alopecia (AGA) in male and female patients. We also assessed the normal value of hair count in scalp biopsy specimen from Iranians and compared with published data," scientists in Iran report. "Thirty subjects with clinically normal scalps, 25 male and 28 female patients with AGA were studied. Vertical and horizontal sections of 4-mm punch biopsy specimens were examined at various levels from the papillary dermis to the subcutis. Hair counts of total, terminal, vellus, anagen and telogen hairs were obtained by ocular micrometer. Hair counts were not significantly different from published data in American Whites but significantly higher in Iranians compared with Koreans (p <0.001). There was no significant difference between male and female patients with AGA. Perifollicular inflammation was lower in both the normal subjects and the patients compared with other studies. In AGA patients, total and vellus hairs were lower and terminal to vellus (T:V) ratio was higher than the results of previous studies in Whites (p <00.1). T:V ratio of control group was significantly higher in this study compared with previous published data," wrote F.S. Aslani and colleagues, . The researchers concluded: "Perhaps the higher ratio than the reported data could means the onset of miniaturization." Aslani and colleagues published their study in the Journal of Cutaneous Pathology (Hair counts in scalp biopsy of males and females with androgenetic alopecia compared with normal subjects. Journal of Cutaneous Pathology, 2009;36(7):734-9). For additional information, contact F.S. Aslani, Shiraz Univeristy of Medical Science, Dept. of Pathology, Shiraz, Iran. The publisher's contact information for the Journal of Cutaneous Pathology is: Blackwell Publishing Inc., 350 Main St., Malden, MA 02148, USA. Keywords: Iran, Alopecia Genetics, Alopecia, Biopsy, Cutaneous Pathology, Surgery. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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