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New Paget's Disease Data Have Been Reported by G. Baiocchi and Co-Authors

"Few reports have described conservative treatments for vulvar Paget disease. Our aim was to evaluate the efficacy of conservative treatment with imiquimod. We performed a retrospective analysis of 4 patients who were treated with topical imiquimod 5% cream. One patient underwent vulvectomy after imiquimod therapy, and 3 patients experienced extensive recurrent disease that was unsuitable for surgical resection and were treated successfully with imiquimod," wrote G. Baiocchi and colleagues.

The researchers concluded: "Imiquimod is an effective therapeutic agent for the conservative treatment of vulvar Paget disease."

Baiocchi and colleagues published the results of their research in the Journal of Lower Genital Tract Disease (Conservative Management of Extramammary Paget Disease With Imiquimod. Journal of Lower Genital Tract Disease, 2012;16(1):59-63).

For additional information, contact G. Baiocchi, Hosp Canc AC Camargo, Dept. of Pathol, BR-01509010 Sao Paulo, Brazil.

The publisher of the Journal of Lower Genital Tract Disease can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St, Philadelphia, PA 19106-3621, USA.

Keywords: City:Sao Paulo, Country:Brazil, Region:South America, Antiretrovirals, Drugs, Topical Agents, Dermatological Agents, Topical Antiinfectives, Extramammary Paget's Disease

This article was prepared by Biotech Week editors from staff and other reports. Copyright 2012, Biotech Week via NewsRx.com.